In 1901 Balsamo Stella began working in a painter's studio in Ca 'Pesaro but because the local Municipality, contrary to the will of Duchess Felicita Bevilacqua La Masa, demanded the payment of rent, Guido left after less than two and a half years.
From 1909 Balsamo Stella attended the Academy of Fine Arts in Munich where he was taught by Albert Welti, Arnold Böcklin's student.
[5] Upon his return to Italy Balsamo Stella first lived in Florence where from 1922 he taught at the Royal Institute of Art of S. Croce; he also set up a glass laboratory in Colle Val d'Elsa.
In 1929 Balsamo Stella worked in Murano at SALIR (Studio Ars Labor Industrie Riunite).
[6] In 1929 Balsamo Stella was called to Monza to head the prestigious ISIA (Higher Institute for Artistic Industries) where he remained until 1932.