Guiglia (Frignanese: Guîa or Guéa) is a comune (municipality) in the Province of Modena in the Italian region Emilia-Romagna, located about 30 kilometres (19 mi) southwest of Bologna and about 25 kilometres (16 mi) south of Modena.

Guiglia borders the following municipalities: Valsamoggia, Marano sul Panaro, Pavullo nel Frignano, Savignano sul Panaro, Zocca.

Among its churches is San Geminiano, Guiglia and San Giovanni Battista, Pieve di Trebbio.

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