From West to East it runs approximately 80 kilometres (50 mi) from Boca de Tinajones, mouth of Sinú River, in Córdoba, to Punta San Bernardo (San Bernardo Point) in Sucre.
The coastline of the Gulf of Morrosquillo is shared by the departments of Sucre and Córdoba on the north of Colombia.
The main city on the gulf is Tolú; five kilometers away from Tolú is "Las Playas del Francés" (The Frenchman's Beaches) distinguished because of its wide white sand beaches.
Seventeen kilometers away from Tolú is located the tourist town of Coveñas, where besides the beautiful beaches it is possible to taste the local food and enjoy of the ecotourism by a canoe trip in La Cienaga La Caimanera, a relict of the native animals and plants.
The Rio Sinu used to empty into the Gulf, but since about 1941, it changed course and the beaches are not as large as they had been.