There are plans to build a major deep-water port at the village of Tribugá in the main river estuary.

The municipality of Nuquí, with a population of 7,000, is in the center of the gulf and has an airport, hospital, high school and commercial infrastructure.

[2] Core samples have shown that in the south of the gulf dominant populations of Rhizophora mangroves have been relatively stable for the last 4,500 years.

[3] Land animals include bats, marsupials, anteaters, sloths, jaguars, pumas, otters, coatis, bush dogs, snakes, poison frogs and iguanas.

There is a rocky sea bed, small corals, large schools of fish, and great diversity and color.

[7] The documentary film Expedicion Tribugá was released in November 2020, featuring scientists researching the local biodiversity and the inhabitants of the gulf explaining their concerns over the building of the port.

[8] As part of the Expedicion Tribuga project, the gulf was declared a biodiversity "Hope Spot" by Mission Blue, an organization led by ocean scientist Dr. Sylvia Earle.