She has appeared in Hindi, Telugu, Tamil, Marathi,[2] Kannada and Punjabi films.

[4] Gurleen Chopra made her debut as a model in famous song by Surjit Bindrakhiya 'tedi tedi takdi tu' in 1999.

Gurleen Chopra made her debut in the Hindi film, Indian Babu.

[5] Her next Hindi film was Kuch To Gadbad Hai, in which she played an orphan girl Riya.

[5] After a long hiatus, she signed a Telugu film titled Konaseemalo Chittemma Kittayya in 2009.