Gustave Malécot (28 December 1911 – November 1998) was a French mathematician whose work on heredity had a strong influence on population genetics.
Malécot grew up in L'Horme, a small village near St. Étienne in the Loire département, the son of a mine engineer.
His work focused on R.A. Fisher's 1918 article The Correlation Between Relatives on the Supposition of Mendelian Inheritance.
Between 1940 and 1942, with France under Nazi German occupation, Malécot taught mathematics at the Lyceé de Saint-Étienne.
In 1945 he joined the Université de Lyon, becoming professor of applied mathematics in 1946, a position he held until his retirement in 1981.