HCT116 cells

HCT116 is a human colon cancer cell line used in therapeutic research and drug screenings.

[1] HCT116 cells have a mutation in codon 13 of the KRAS proto-oncogene, and are suitable transfection targets for gene therapy research.

[5] HCT116 cells are used in a variety of biomedical studies involving colon cancer proliferation and corresponding inhibitors.

The cell line has been used in tumorigenicity studies, along with other research that has shown that Cyclin D1 holds large importance for the activity of lithocholic acid hydroxyamide.

The Insp8 gene is part of a cell's energy metabolism process, and can affect the cellular phenotype as a result.