311814960ENSG00000237541ENSG00000223793ENSG00000233192ENSMUSG00000036594P01906P04228P14436P04227NM_020056NM_010378NP_064440NP_034508HLA class II histocompatibility antigen, DQ(6) alpha chain is a protein that in humans is encoded by the HLA-DQA2 gene.

Also known as HLA-DXA or DAAP-381D23.2, it is part of the human leukocyte antigen system.

[5] The protein encoded by this gene is expressed, but unlike HLA-DQA1, it is apparently unable to heterodimerize with HLA class II beta chain paralogues.

[6] The low level of HLA-DQA2 expression is apparently due to impaired transcription factor binding to the HLA-DQA2 gene promoter.

[7] Transcriptome analysis of blood immune cells and nasopharyngeal cells before elaborate infection of study participants revealed that heightened expression of HLA-DQA2 correlates to a significantly lower chance of COVID-19 successfully infecting the individual.