HLA-DR8 (DR8) is a HLA-DR serotype that recognizes the DRB1*0801 to *0807, and *0810 to *0812 gene products.
The serological reaction of DR8 is relatively good.
The serology of DRB1*0808, *0809 and *0813 to *0832 serotypes is unknown.
DR8 is linked to papillary thyroid carcinomas,[3] early onset pauciarticular juvenile chronic arthritis,[4][5] primary biliary cirrhosis[6] HLA-DRB1*0801 is linked to primary biliary cirrhosis[7] In Mexicans DR8 is found more often in type-2 juvenile diabetes.
[8] HLA-DRB1*0803 is also linked to primary biliary cirrhosis[7] HLA-DR8 is not genetically linked to HLA-DR51 to DR53, but is linked to DQ4 serotypes.