HMS Fame was a 74-gun third rate ship of the line of the Royal Navy, built at Deptford Dockyard.

[1] She was constructed on the same building slip as was HMS Courageux, her keel having been ordered to be laid down on it immediately after the other ship's launch on 26 March 1800.

[1] In November 1808, whilst under the command of Captain Bennet, Fame joined a squadron lying off Rosas, where Captain Lord Cochrane was assisting the Spanish in the defence of Castell de la Trinitat against the invading French army.

Boats from Fame helped evacuate Cochrane's garrison forces after the fort's surrender on 5 December.

[2] On March 4, 1811, Argentine lawyer and journalist Mariano Moreno died on this ship while travelling on a diplomatic mission to England, his body was thrown into the water wrapped in a Unión Jack flag.