The second HMS Seymour (K563) was a British Captain-class frigate of the Royal Navy in commission during World War II.

The ship was laid down as the unnamed U.S. Navy destroyer escort DE-98 by Bethlehem-Hingham Shipyard, Inc., in Hingham, Massachusetts, on 1 September 1943 and launched on 1 November 1943.

[2] Commissioned into service in the Royal Navy as the frigate HMS Seymour (K563) on 23 December 1943 simultaneously with her transfer, the ship served on patrol and escort duty for the remainder of World War II.

[1][2] She sank the German motor torpedo boat S-220 – an S-boat, known to the Allies as an "E-boat" – on 1 March 1945.

[2] The U.S. Navy struck Seymour from its Naval Vessel Register on 25 February 1946.