Following shakedown off Bermuda, Odum transited the Panama Canal and proceeded up the Pacific coast to San Diego, California, whence she departed on 16 May 1945 for Hawaii.

There she completed amphibious warfare training off Maui, took on underwater demolition team gear, and headed to the Western Pacific for World War II service.

Discharging her cargo at Guam, she proceeded to Ulithi Atoll, whence she escorted transport SS Kote Baroe to Leyte in the Philippine Islands, arriving there on 29 June 1945.

Assigned to the United States Atlantic Fleet, she operated in Transport Squadron 2 along the United States East Coast and off Cuba and Puerto Rico until entering the Charleston Naval Shipyard at Charleston, South Carolina, for inactivation on 26 July 1946, after which she proceeded to Green Cove Springs, Florida for decommissioning.

Odum decommissioned at Green Cove Springs on 15 November 1946 and entered the Florida Group of the Atlantic Reserve Fleet on the St. Johns River there.