3R27, 3TO8319115388ENSG00000104824ENSG00000282947ENSMUSG00000015165P14866Q8R081NM_001005335NM_001533NM_177301NP_001005335NP_001524NP_001389868Heterogeneous nuclear ribonucleoprotein L is a protein that in humans is encoded by the HNRNPL gene.

[5][6] Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogeneous ribonucleoprotein (hnRNP) complexes.

Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA.

Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex.

Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm.