[5] This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).

The hnRNP proteins have distinct nucleic acid binding properties.

The protein encoded by this gene has two RRM domains that bind to RNAs.

The protein encoded by this gene is similar to its family member HNRPD.

[5] Heterozygous nonsense mutations in HNRNPDL has been identified as the cause of the autosomal disorder, Limb-girdle muscular dystrophy.