Commonly known as the Port Macquarie funnel-web spider,[1] Hadronyche macquariensis was described by Mike Gray in 2010, the holotype male having been collected from Taree, New South Wales in January 1978.

[2] Within the genus, it is a member of the infensa group, which contains several described and undescribed species in central New South Wales and southern Queensland.

[2] The Port Macquarie funnel-web spider is found along the northern coast of New South Wales in eastern Australia, where specimens have been collected from the vicinity of Forster north through Taree, Port Macquarie to Coffs Harbour and Bellingen.

[2] The Port Macquarie funnel-web spider has been responsible for at least one case of serious envenomation out of six bites that can be attributed to it.

[3] A six-year-old boy was bitten on the foot in sand dunes near Forster and required hospitalisation and intubation.