Baptiste made her WTA Tour main-draw debut at her hometown tournament, the 2019 Washington Open and defeated Grand Slam finalist and former top-ten player, Madison Keys.

At the 2024 French Open, she entered the main draw as a lucky loser[5] and defeated Kayla Day for her second win at this major.

With her second round win over seventh seed Barbora Krejčíková at the 2024 Wuhan Open as a qualifier, Baptiste became the first player ranked outside the top 100 (at No.

[8] Baptiste made her World TeamTennis debut in 2020 with the Vegas Rollers as an alternate, later ending up on the roster for the New York Empire in the 2020 season at The Greenbrier.

[9] Only main-draw results in WTA Tour, Grand Slam tournaments, Fed Cup/Billie Jean King Cup and Olympic Games are included in win–loss records.