He held several positions in Akbar's service, and served as the Mughal ambassador to Abdullah Khan II of Bukhara.

During this period, 'Abdu'r Razzaq was also imprisoned, and his sons migrated to the Mughal Empire in present-day India.

[4] Akbar appointed him to the board of authors of Tarikh-i Alfi, a history of the first thousand years of Islam.

[7] Humam's elder son Kamal al-Din, born at Fatehpur Sikri and better known as Hakim Hadhiq, gained prominence as a poet and prose-writer.

[2] His other son, Hakim Khushhal, held the mansabdar rank of 6000 soldiers, and served as a bakhshi (military paymaster) and waqianawis(court writer) in the Deccan region.