Hamilton Secondary College offers learning in all areas of the mandated curriculum, with comprehensive ICT, science and visual arts programs.

Students with disabilities are catered for with individual programs within the purpose-built Hamilton Unit.

The amalgamation of Glengowrie High School and Mitchell Park Boys Technical College in 1991 prompted the school to be renamed Hamilton, after the Hamilton family, prominent winegrowers in the area.

[4] In November 2021 the school opened a new building and revamped several other buildings to allow for incoming students, including those involved in the transition of year 7 students from primary to secondary schools.

[5] In a 1999 article written by Bronwyn Hurrell and published in The Advertiser, Professor Julie James Bailey, author of Reel Women: Working in Film and Television and former Professor of Film and Media at Griffith University, says she 'came across the media course at Hamilton Secondary College and was extremely impressed,' pointing out that ‘It’s the only (course) that feeds into the commercial TV stations having some knowledge of equipment.