The pizzeria was located on Killingsworth Street in northeast Portland's Vernon neighborhood and shared a space with Seastar Bakery.

[1][2] Handsome's pizzas were "New York-Neapolitan hybrids" and featured sourdough crusts, baked in a custom-built, wood-fired oven.

[3][2][6] During a gap between the two locations, Handsome hosted a series of pop-ups at the bakery Tabor Bread.

[14] The newspaper's Samantha Bakall included the pizzeria in a list of Portland's best wood-fired pizza.

[17] In 2021, Brooke Jackson-Glidden included Handsome in Eater Portland's overview of eateries for "exceptional" pizzas in the city and said the "hyper-seasonal specials are often stunners".