[2] Prior to her political career, Bruins Slot served in the Royal Netherlands Army; she was deployed to Uruzgan Province, Afghanistan.

She focused her work as a parliamentarian on matters of defence personnel, local government, healthcare science, medical law, psychiatry and sports.

From 2019 to 2022, Bruins Slot was a member of the provincial executive of Utrecht, in which she was in charge of nature, agriculture, soil and water, sport and governance.

[6] The following month, Bruins Slot said that the Netherlands would not object if Ukraine used Dutch-supplied F-16 fighters to strike targets inside Russia.

[7] She returned to the Royal Netherlands Army in February 2025, after her term as Minister of Foreign Affairs had ended, in the rank of major general.