Within the normal reproductive cycle, haploidisation is one of the major functional consequences of meiosis, the other being a process of chromosomal crossover that mingles the genetic content of the parental chromosomes.
[1] Usually, haploidisation creates a monoploid cell from a diploid progenitor, or it can involve halving of a polyploid cell, for example to make a diploid potato plant from a tetraploid lineage of potato plants.
If haploidisation is not followed by fertilisation, the result is a haploid lineage of cells.
Haploidisation was one of the procedures used by Japanese researchers to produce Kaguya, a mouse which had same-sex parents; two haploids were then combined to make the diploid mouse.
Haploidisation commitment is a checkpoint in meiosis which follows the successful completion of premeiotic DNA replication and recombination commitment.