It is managed by Harrogate and District NHS Foundation Trust.

[1] In the 1970s work began to build a modern replacement facility on Lancaster Park Road.

[1] The first phase, which consisted of an accident and emergency department, some laboratories and a few wards, was opened by Princess Margaret in January 1975.

[2] The Queen and the Duke of Edinburgh visited the site later that year to celebrate the completion of the hospital and to conduct the official opening of the Strayside wing.

[2] The Sir Robert Ogden Macmillan Cancer Centre was completed in 2014 and Prince Charles and the Duchess of Cornwall made an official visit to it in 2016.