Haruhime (媛姫, 1641 – 28 July 1658)[1] was the daughter of Hoshina Masayuki, granddaughter of Tokugawa Hidetada and great-granddaughter of Tokugawa Ieyasu.
In 1654, she married Uesugi Tsunakatsu, the third head of the Yonezawa Domain.
They had no children, so they adopted a son of Tsunakatsu's younger sister with Kira Yoshinaka.
She died in 1658 because she was poisoned by her mother, Shoko-in (1620–1691).
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