Harvey Lodish

Harvey Franklin Lodish (born November 16, 1941) is a molecular and cell biologist, professor at the Massachusetts Institute of Technology (MIT), Founding Member of the Whitehead Institute for Biomedical Research,[1] and lead author of the textbook Molecular Cell Biology.

Sydney Brenner and Francis Crick (winners of the Nobel Prize in Physiology or Medicine, 2002 and 1962, respectively), he joined the faculty of the MIT Department of Biology.

He was Chair of the advisory board of the Division of Basic Sciences of the Fred Hutchinson Cancer Center and of the Lerner Research Institute of the Cleveland Clinic.

He has served on the advisory boards of several other institutions, including the Biozentrum of the University of Basel, the European Molecular Biology Laboratory in Heidelberg, the Center for Molecular Biology Heidelberg (ZMBH) in Germany, the Life Sciences Institute of the University of Michigan, and the PEW Scholars Program in Biomedical Sciences.

And with two former students he founded Carmine, which develops red cell extracellular vesicles as gene delivery vehicles.

[4] Initially, Dr. Lodish's work focused on translational control of protein synthesis and on development of the cellular slime mold Dictyostelium discoideum.

Beginning in 1973, his laboratory has concentrated on the biogenesis, structure, and function of several important secreted and plasma membrane glycoproteins.

He defined the biosynthesis and maturation of the vesicular stomatitis virus and other plasma membrane glycoproteins, identified the intracellular organelles that mediate recycling of the asialoglycoprotein and transferrin receptors, and clarified the role of pH changes in delivery of iron to cells and recycling of the transferrin receptor.

Two former postdoctoral researchers in Dr. Lodish's laboratory have gone on to win Nobel Prizes: Aaron Ciechanover (Chemistry, 2004) and James Rothman (Physiology or Medicine, 2013).