Isomaltase

Isomaltase (EC 3.2.1.10) is an enzyme that breaks the bonds linking saccharides, which cannot be broken by amylase or maltase.

The product of the enzymatic digestion of alpha-limit dextrin by isomaltase is maltose.

Isomaltase helps amylase to digest alpha-limit dextrin to produce maltose.

The human sucrase-isomaltase is a dual-function enzyme with two GH31 domains, one serving as the isomaltase, the other as a sucrose alpha-glucosidase.

Sucrase-isomaltase’s mechanism results in a net retention of configuration at the anomeric center.