Renowned Lebanese writer George Jordac, describes al-Shirazi as 'a clear mind, honest tongue, and lovable heart with a face that reflects the light of a generous soul'.

[7][4] In 1963, during an annual function held in Karbala, commemorating the birth of Ali, al-Shirazi recited his renowned poem, za'imuna al-karrar (transl.

He also insults Aflaq by saying:[8] أو ليس قـد سمّاه يَـعربُ عفلقا ولــديــه أحقــــاد الصــليب دمــاء وأبــــوه جــاء لســوريا مستــعمراً والأم بــــــاريــــســـيـــة عـــجـــمـــاء Did Ya'rub not call him Aflaq Whilst he holds the grudges of the crusaders His father came to Syria as an imperialist Whilst his mother is a foreign Parisian Because of this poem, al-Shirazi began to face pressures from the Baathists, that led to his immigration to Lebanon in 1964.

[10] Through al-Shirazi's numerous visits to Saudi Arabia for the annual Hajj, he met with officials and the Muslim World League, and through them, in 1972, he managed to meet with King Faisal, where he discussed beginning the conversation in regards to rebuilding the Baqi cemetery.

[11] Murtadha al-Qazwini states that upon meeting Mohammed Suroor Sabban, he told him "the current wall that surrounds the cemetery was built due to the efforts of Muhammad al-Shirazi and his brother Hassan.

He set up the Imam al-Mehdi school for religious studies in Lebanon and in Syria, he founded the Zaynabiya Islamic Sciences Seminary in Sayyeda Zainab in 1975.

[13][14] On Friday, 2 May 1980, al-Shirazi was on his way to Borj El Brajneh to attend the funeral of Muhammad Baqir al-Sadr, who was assassinated in Iraq at the hands of the Baathists along with his sister, Bint al-Huda.

[9] His corpse was transferred to Qom, Iran, where Ayatollah Marashi Najafi led the funeral prayers, and al-Shirazi's body rested in the Fatima Masumeh Shrine.