[2] HealthSense's President is Nick Ross and its patrons include Lord Dick Taverne, Steve Jones, Margaret McCartney, Sir Michael Rawlins and the comedian Robin Ince.

It publishes the quarterly HealthSense Newsletter and occasional "position papers" on controversial medical treatments.

It was inspired by the oncologist Michael Baum, clinical pathologist and biochemist Vincent Marks, medical journalist Caroline Richmond and others, and began as the Campaign Against Health Fraud mostly targeting unfounded claims by proponents of alternative medicine and downright quackery, but soon broadened to audit all forms of medical practice, and many of its members are more concerned about unproven orthodox therapies than complementary ones.

Nonetheless it still sometimes attracts criticism from some believers in alternative medicine who claim that scientific approaches cannot be applied to their way of working.

HealthSense maintains it has no commercial sponsors of any form and relies on membership fees and donations from other charities.