It delivers medical care on behalf of the Government of Prince Edward Island's Department of Health and Wellness and is governed by a board of directors appointed by the Minister of Health and Wellness.
Board members are Diane Griffin (chair); Peter MacDonald (vice chair); Dr. Richard Wedge; Helen Flynn; Colleen Parker; Megan Cheverie; Selvi Roy; Dr. William Montelpare and Jennifer Evans.
As part of their role in managing the affairs of Health PEI, they employ the chief executive officer.
Board committees are: Quality and Safety, Audit, Risk & Planning and Human Resources.
Following the release of a 2008 report by Corpus Sanchez International titled "A Call to Action: A Plan for Change", work began to integrate Prince Edward Island's health services.