[2] After her father's death in 1477, eight-year-old Hedwig was placed under the guardianship of her cousin, Casimir II.
On 11 August 1483 she married the widower Stephen Zápolya, Lord of Trencsén (Trenčín).
Hedwig remained in Hungary, where she managed the huge property left behind by her late husband.
[4] She was also a generous supporter of the Carthusian monastery of Lapis Refugii in Spiš.
[5][1] Hedwig died on 16 April 1521 in Trencsén Castle and was buried alongside her husband in the Zápolya family vault on the Szepes chapter house.