Heinrich Dernburg (3 March 1829 – 23 November 1907) was a German jurist, professor, and politician.

Born in Mainz, Grand Duchy of Hesse, he was the brother of Friedrich Dernburg [de] and the maternal grandfather of the historian Heinrich Sproemberg.

With Brinckmann and others he founded in 1851 the Kritische Zeitschrift für die Gesammte Rechtswissenschaft.

Dernburg was one of the leading experts for Prussian civil law as codified in the ALR.

Unlike other Pandect scholars of his time, Dernburg was never accused of advocating a doctrinary and reactionary form of legal positivism.