She was born to a Danish mother and an aristocratic Gambian father who belonged to the Joof dynasty.

Her feature film debut En kort en lang was seen by ten percent of the Danish population, and her second feature Oh Happy Day, was sold to Disney for a US remake.

[3] She has hosted Bullerfnis and other children's TV-programs, but was also the voice of the title character in the hardcore pornographic film Constance (1998).

As an actress, Joof is best known for award-winning performances as supporting characters in such comedies as Hannibal & Jerry (1997), Den eneste ene (1999), and Humørkort-stativ-sælgerens søn (2002).

was aired in Latin America, the United States and Africa by the TV channel Eurochannel.