He served at different times as attorney general[1][2] (from October 1695[2]), judge of the supreme court, and President of the Council, making many judicial reforms.
[2] In 1699, after the death of Harvey, Walker was named the Acting Deputy Governor of North Carolina.
[1][2] However, the English Crown sought to weaken proprietary colonies, so Walker was often forced to decide whether to help the Lords Proprietors or to support the monarch.
They were charged with "destroying and burning their stock and timber houses, refusing to pay tribute" and to accept government laws.
That year, Henderson Walker resigned from the governor's office, replaced by Robert Daniel.
[3] Although he was originally buried at his plantation, located near the Albemarle Sound, he was later reburied in the graveyard at St. Paul's Church, Edenton.