Henningsleben (pronounced [ˈhɛnɪŋgsˌleːbn̩]) is a village and an Ortsteil (part) of the town of Bad Langensalza in Thuringia, central Germany, with about 230 inhabitants.

South of Nägelstedt, the stream flows into the Tonna, 550 metres (1,800 ft) before its confluence with the Unstrut.

The Bundesstraße (federal highway) B 247 between Gotha and Bad Langensalza runs along the eastern edge of the village.

The paved field path Illeber Weg leads from the B 247 straight northeast to Illeben, about 3 kilometres (1.9 mi) away.

In 1952, the second Landwirtschaftliche Produktionsgenossenschaft ("Agricultural Production Cooperative") in the then GDR (after the one in Merxleben) was founded in Henningsleben.