De Bettignies was educated at Sorbonne, Catholic University of Paris, and at Harvard Business School.
He was given a professorship in 1975, and started and developed INSEAD's activities in Japan and the Asia Pacific region,[3] leading to the creation of the Euro-Asia Centre (1980), of which he was director general (1980–1988).
He is currently developing the Ethics initiative at INSEAD, and leads the AVIRA program for business leaders, which brings together chairmen and CEOs from about 30 countries for leadership training.
He teaches the MBA courses on Ethics and Global Business, and Culture and Management in Asia at Stanford and INSEAD.
De Bettignies books include: He is also co-author of: He has published more than 50 articles in business and professional journals.