Henry Burd Cassel (October 19, 1855 – April 28, 1926) was a Republican member of the U.S. House of Representatives from Pennsylvania.

Henry B. Cassel was born in Marietta, Pennsylvania, where he attended Columbia Classical Institute.

Cassel was elected as a Republican to the Fifty-seventh US Congress to fill the vacancy caused by the death of Representative Marriott Brosius.

In 1909, Cassel was convicted of fraud related to the construction of the Pennsylvania State Capitol.

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