He started his medical practice in West Virginia's coal region, moving to Twin Falls, Idaho in about 1922.

[5] According to Bieler, "Discarding the germ theory of disease opened the way for me to explore new methods of eliminating the stagnating waste products from the body.

[5] Bieler was often at odds with the American Medical Association because he believed that drugs are harmful and advised his patients to avoid them.

[3] Deutsch noted that Bieler's statements about food "cures" were spurious and he had made basic mistakes because his research on the topic never went through peer-review.

[2] His treatment of actress Allison Hayes was associated with a continued decline in health, later found to result from lead contamination in a bone meal supplement.

[8] In 1965, Bieler wrote the book Food is Your Best Medicine, published by Random House, a compilation of over fifty years of work treating disease by diet.

"[9] At the time of his death in 1975 he was working on a book called The Incurables, dedicated to the memory of Martin F. Fischer one of his professors from medical school whom he greatly respected.

The book dealt with specific diseases like cancer, lupus, diabetes, asthma, epilepsy, gout, and even the common cold.