Henry Lewis Whitfield (June 20, 1868 – March 18, 1927) was an American politician who was Governor of Mississippi from 1924 until he died in 1927.

Governor Anselm J. McLaurin appointed Whitfield to state superintendent of education in 1898.

Whitfield was elected governor in 1923, narrowly defeating Theodore G. Bilbo.

As governor, Whitfield recommended various progressive programs such as improving the mental health care system and public schools.

While he could conduct business, his condition worsened, and he died in the Governor's Mansion.