It is one of eight wilderness areas in the Mark Twain National Forest[2] and is within the Ava-Cassville-Willow Springs ranger district, about 10 miles (16 km) northeast of Branson, Missouri.

The high points of Coy Bald and Pilot Knob stand 600 feet above Long Creek and offer splendid views of the drainage.

prickly pear cacti, roadrunner, scorpions, collared lizard, pygmy rattlesnakes, and even tarantulas call Hercules Glades Wilderness home, not to mention other wildlife more common in Missouri like the white-tailed deer and wild turkey.

Depending on past land-use histories (fire, grazing, and logging primarily) some places within Hercules Glades Wilderness exhibit floral diversities that rival other areas in Missouri.

[3] The trails lack bridges when crossing the various shallow creeks within the wilderness area.