She graduated with highest honors from Louisville High School in Woodland Hills, California and magna cum laude from California State University, Northridge, where she earned a Bachelor of Arts in Radio, TV and Film with an emphasis in screenwriting.
Salvatore's first big break came with the role of Kelly Phillips in the Nickelodeon series The Secret World of Alex Mack.
She has guest-starred on many television programs, including The West Wing, Without a Trace, Easy Streets, 18 Wheels of Justice, Promised Land, NCIS, Dharma and Greg and many others.
On the big screen, she has had featured roles in films such as American Pie, Bring It On and Charlie Wilson's War.
On October 22, 2005, Salvatore married Jack Angelo, a Los Angeles-based screenwriter and director.