Hoedekenskerke is a village in the Dutch province of Zeeland.

It is a part of the municipality of Borsele, and lies about 22 km east of Middelburg.

The village was first mentioned around 1280 as Hoedekinskerke, and means "(private) church of Oedekin (Oede)".

[3] Hoedekenskerke is a road village along the Westerschelde which developed in the 12th century.

The church was damaged during World War II, and restored between 1948 and 1949.