Hollis Thomas Jr. (born January 10, 1974) is a former American football defensive tackle.

When healthy, Thomas was considered an important part of the Saints' defense, especially against running plays, and he was seen as playing a key role in the Saints' successful 2006 season, when they reached the NFC championship game for the first time in their history.

[1] On December 5, 2006, Thomas was suspended for four games by the NFL for violating the league's steroids policy.

Thomas tore his right triceps on August 14, 2008, in a pass-rushing drill against a Houston Texans offensive lineman.

Thomas was signed by the Carolina Panthers on October 1, 2009, after the team waived defensive tackle Ra'Shon Harris.