MCAS, ACT, and SAT scores of Holliston High School students are consistently well above both state and national averages.

Hollis Seminary (The Cutler School was later built on its charred remains).

The current school building on 370 Hollis Street opened in September 1969.

It consists of a large building containing an auditorium, field house, and lab spaces.

Its departments are: Mathematics and Business, Science and Technology, English, Social Studies, Foreign Language, and The Arts.

It teaches Spanish, French, Latin, and Mandarin Chinese as foreign languages, and offers musical, drama, and studio arts.

In 2010, the team won the MIAA Division III-A Super Bowl.