[9] On November 2, 1965, voters in ten Massachusetts communities approved a referendum to form the Montachusett Regional Vocational Technical School District,[10][11] including the cities of Fitchburg and Gardner, as well as the towns of Royalston, Winchendon, Ashburnham, Ashby, Barre, Phillipston, Hubbardston, Holden, Princeton, and Lunenburg.

On July 18, 1966, the architecture firm of Korslund, LeNormand, and Quann of Norwood was selected to design the new school's facilities.

[10] Six years in planning and construction, the Montachusett Regional Vocational Technical School was approved for occupancy and opened its doors to about 600 students in September 1971.

On May 17, 2000, the school dedicated the $17 million state-of-the-art addition, including the performing arts center, new gym and new classrooms.

From 2007 to 2014, student performance on the Massachusetts Comprehensive Assessment System rose in English language arts from 65% to 95%, and in mathematics, from 62% to 74%.

[19] The school had developed data teams of instructors who analyzed the results and made changes in educational strategies, also promoting collaboration between academic and vocational courses.

A total of 9 experiments have been conducted including some milestone flights on the final Space Shuttle Atlantis and the first SpaceX commercial rocket.