A proposed U-shaped design was planned, with the two wings housing the middle and high schools, and the central core accommodating the auditorium, gymnasium, and cafeteria.

[7] Courses are offered on four levels: Advanced Placement (AP), Honors, College Preparatory, and Life Skills – Vocational.

Graduation requirements include passing scores on the MCAS (Massachusetts Comprehensive Assessment System) in areas of English, Language Arts, Mathematics, and Biology.

[9] The following AP courses were offered in the 2021 – 2022 academic year:[10] Tahanto Regional High School received the District E Sportsmanship Award in 2009 and 2021.

The team won the D4 Central Massachusetts District Championship in 2017, beating Sutton 8–7, making this the school's second baseball title, and its first since 1993.

In the spring of 2021, the girls lacrosse team made their varsity debut and finished with a perfect 10-0 record in regular season play.

The high school offers fall, winter and spring sports programs that include girls' and boys' soccer, field hockey, basketball and softball.

Also offered are golf, boys' and girls' lacrosse, cross country, football, cheerleading, baseball, wrestling, tennis, gymnastics, ice hockey, and track and field.