It was set up on 9 April 1945 by the Society of the Holy Child Jesus (SHCJ) and run by the Roman Catholic Archdiocese of Lagos.

It is located in South-West Ikoyi on the cusp of Obalende and Keffi; next to its brother school St Gregory's College, Lagos.

The Society founded Holy Child College, Lagos in 1945 at the invitation of Archbishop Leo Taylor, who wanted a good Catholic secondary school for the girls in his archdiocese.

[citation needed] Holy Child College offers an all-round academic education as well as Sports, Oratory Skills, Latin, Art and Drama, Etiquette and Deportment.

[citation needed] - Bimbo Odukoya,(1960-2005) Pastor, writer, co-founder of Fountain of life church, Singles and Married Ministry.