[2] One of the few Catholic hospitals in Utah for over a century, it was sold by the Sisters of the Holy Cross in 1994 to the for-profit institution, HealthTrust.

[3] Due to antitrust concerns raised by the Federal Trade Commission, the hospital was then sold to Champion Healthcare Corporation in 1995.

[citation needed] Subsequently, Iasis Healthcare managed the medical center between 2001 and September 2017.

[5][6] In May 2023, Salt Lake Regional Medical Center was acquired by CommonSpirit Health.

In 1976 Holy Cross Chapel was added to the state historic registry and now serves as a nondenominational interfaith sanctuary.