It was approved and accredited by the Middle States Association of Colleges and Secondary Schools, the Commonwealth of Pennsylvania, and the Diocese of Allentown.

Holy Name High School traced its inception to St. Peter’s Roman Catholic Church located in Reading.

The original tract of land comprised 35.6 acres (144,000 m2) in all and is bounded on the north by Joan Terrace, on the east by the Swartz Tract (presently occupied by Baldwin Hardware (a division of Black and Decker), on the south by East Wyomissing Boulevard, and on the west by Parkside Drive South.

On Sunday, August 30, 1964, Holy Name High School was dedicated by His Excellency The Most Reverend Egidio Vagnozzi, D.D., Apostolic Delegate to the United States.

In March 1995, it was announced that the Oblates would be leaving Holy Name High School and that Sister Joseph Eleanor Murphy, IHM, would be the new Principal.

As the result of a major capital campaign, a renovation and construction project was undertaken in the spring of 1997, which would be completed in several different phases over the next few years.

Holy Name offered a core curriculum around English, Mathematics, Foreign Languages, Sciences, Social Studies, and Theology.

AP courses in English, Calculus, Statistics, Physics, Biology, Chemistry, and Western European History were offered.