Until October 2013 it operated route services until these passed to Transit Systems.

Hopkinsons' origins can be traced to 1923 when the Try family, trading as Merrylands Bus Company, commenced operating services in the Fairfield, Guildford and Merrylands area with four buses.

[2][3] From 2005 Hopkinsons' services formed part of Sydney Bus Region 3.

[7][8][9] Having downsized, the depot in Smithfield closed in June 2020 with the remaining vehicles relocated to that of sister company Premier Charters in Helensburgh.

Initially operating Dennings and later Austral Tourmasters, it has since moved to Scania and Volvos.