The number of in-patients is the sum of patients which changed not only by the newly diagnosed hospitalized and those who died among in-patients, by other factors such as the number of patients who escaped or were discharged, depending on the condition of the times.

Recently they were encouraged to be discharged, but the long period of the segregation policy causing leprosy stigma might influence the number of those who went into the society.

It was at the congress of the Japanese Leprosy Association held in the Keiaien Sanatorium on November 2 and 3, 1947 that the effects of promin were first reported.

At first it did not attract attention since cepharanthin, a new drug for leprosy which had been tested earlier proved disappointing.

Leprosy in earlier days has been associated with scabies, and this has been pointed out by Kensuke Mitsuda.