It belongs to the Servicio Madrileño de Salud, the health service of the Community of Madrid.

It was crested in 1990 from the merger of three previous hospitals, and was established as a center of excellence in research and treatment of infectious diseases.

[3] On 21 September it was announced that Brother Manuel García Viejo, another Spanish citizen who was medical director at the St John of God Hospital Sierra Leone in Lunsar, had been evacuated to Spain from Sierra Leone after being infected with the virus.

[5] On October 6, 2014, Maria Teresa Romero Ramos a nursing assistant who worked at the Hospital Carlos III helping with the care of Manuel García Viejo, arrived at her local hospital, the Hospital Universitario Fundación Alcorcón in Alcorcón, where she was diagnosed with Ebola virus disease.

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